Name | 3'- Methoxy Puerarin |
Synonyms | 3''-METHOXYPUERARIN Puerariaglycoside 3 Methoxypuerarin, 3'- 3'- Methoxy Puerarin 4H-1-Benzopyran-4-one,8-b-D-glucopyranosyl-7-hydroxy-3-(4-hydroxy-3-methoxyphenyl)- 4H-1-Benzopyran-4-one, 8-β-D-glucopyranosyl-7-hydroxy-3-(4-hydroxy-3-methoxyphenyl)- 8-beta-D-Glucopyranosyl-7-hydroxy-3-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one |
CAS | 117047-07-1 |
Molecular Formula | C22H22O10 |
Molar Mass | 446.4 |
Density | 1.583 |
Melting Point | 212-213℃ |
Boling Point | 706.0±60.0 °C(Predicted) |
Specific Rotation(α) | +16.5 (c, 0.2 in DMSO) |
Solubility | Soluble in methanol |
Appearance | Powder |
pKa | 6.30±0.20(Predicted) |
Storage Condition | 2-8℃ |
MDL | MFCD21363095 |
In vivo study | 3'-Methoxypuerarin increases the number of surviving neurons in the hippocampal CA1 region and markedly reduces the number of apoptotic pyramidal neurons after ischemia/reperfusion injury. 3'-Methoxypuerarin can protect hippocampal neurons against I/R injury by inhibiting apoptosis. |
Reference Show more | 1. Yu, Yunru, et al. "Identification of anti-inflammatory compounds from Zhongjing formulae by knowledge mining and high-content screening in a zebrafish model of inflammatory bowel diseases." Chinese medicine 16.1 (2021): 1-14. 2. [IF=3.361] Hongguang Zhang et al."Extraction of isoflavones from Puerariae lobata using subcritical water."Rsc Adv. 2018 Jun;8(40):22652-22658 3. [IF=7.132] Li Yang et al."Supercritical extraction and antioxidant activity of major ingredients in Puerariae lobatae root, Pinus massoniana needle, Citrus reticulata peel and their mixture."J Co2 Util. 2021 Jun;48:101518 4. [IF=5.455] Yu Yunru et al."Identification of anti-inflammatory compounds from Zhongjing formulae by knowledge mining and high-content screening in a zebrafish model of inflammatory bowel diseases."Chin Med-Uk. 2021 Dec;16(1):1-14 5. [IF=4.759] Wenjie Wu et al."An analytical strategy for accurate, rapid and sensitive quantitative analysis of isoflavones in traditional Chinese medicines using ultra-high performance supercritical fluid chromatography: Take Radix Puerariae as an example."J Chromato 6. [IF=3.512] Yan Cheng et al."Comparison of the Extraction Efficiency of Isoflavone Compounds from Puerariae lobatae by Ionic Liquids with 11 Anions and 8 Imidazolium-Based Cations."Acs Omega. 2020;5(15):8962–8971 |